کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1396532 | 1501189 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Stilbene analogs as inducers of apolipoprotein-I transcription
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Stilbene analogs as inducers of apolipoprotein-I transcription Stilbene analogs as inducers of apolipoprotein-I transcription](/preview/png/1396532.png)
چکیده انگلیسی
Based on the naturally occurring stilbene, Resveratrol, a series of novel stilbene derivatives were synthesized, which have the ability to induce the expression of the ApoA-I gene. Several compounds equally or more potent than Resveratrol were identified. trans-4,4′-Dihydroxy-2-methoxystilbene was the most potent (4.6× more potent than Resveratrol). These compounds provide an early lead into new drugs to treat atherosclerosis.
Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 5, May 2010, Pages 2018–2023
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 5, May 2010, Pages 2018–2023
نویسندگان
Henrik C. Hansen, Fabrizio S. Chiacchia, Reena Patel, Norman C.W. Wong, Vladimir Khlebnikov, Renata Jankowska, Kalpesh Patel, M. Madhava Reddy,