کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1397161 1501235 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chemotherapy of leishmaniasis part III: synthesis and bioevaluation of novel aryl substituted terpenyl pyrimidines as antileishmanial agents
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Chemotherapy of leishmaniasis part III: synthesis and bioevaluation of novel aryl substituted terpenyl pyrimidines as antileishmanial agents
چکیده انگلیسی

Some aryl substituted terpenyl pyrimidines 4 (a–p) have been synthesized using novel synthetic methods. The compounds were screened for in vitro antileishmanial activity against promastigotes. Compounds 4c, 4i and 4l showed IC50 values as 35, 35 and 25 μg ml–1.

Aryl substituted terpenyl pyrimidines 4 have been synthesized using novel synthetic methods and were screened for in vitro antileishmanial activity in promastigotes.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 41, Issue 6, June 2006, Pages 779–785
نویسندگان
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