Synthesis of hollow microspheres poly(o-phenylenediamine)/iron oxide composites and application of fluorescence probe in yeast RNA detection

In this communication, we demonstrated that chemical oxidation polymerization of o-phenylenediamine (oPD) by Fe2(SO4)3 at room temperature results in the formation of hollow microspherical PoPD/Fe2O3 composites, which were self-assembled from 2D nanosheets. PoPD/Fe2O3 composites could be used for rapid determination of yeast RNA as a fluorescence probe, based on the fluorescence enhancement of composites in the presence of yeast RNA. The novel morphology of PoPD/Fe2O3 composites synthesized in the research can be used as a new fluorescence probe for sensitive determination of DNA or RNA.