کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1443613 1509457 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immobilization of DNA on nano-hydroxyapatite and their interaction with carbon nanotubes
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Immobilization of DNA on nano-hydroxyapatite and their interaction with carbon nanotubes
چکیده انگلیسی

Here we present a preliminary study on the interaction of bio-molecules (deoxyribonucleic acid (DNA) and nano-hydroxyapatite (HA)) with multi-wall carbon nanotubes (MWCNTs). Initially, nano-size hydroxyapatite was interacted with functionalized carbon nanotubes (FCNTs, HFCNTs) and then 100 base pair (bp) DNA was immobilized (DHFCNTs). Well-known acid treatment was used to functionalize the MWCNTs. The characteristic vibrational and stretching modes of hydroxyl and carbonyl group were observed at 3401, 1632 and 1708 cm−1, validating fucntionalization. The existence of 31P and 1H signals were measured by the solid state NMR spectroscopy for HA, HFCNTs and DHFCNTs which revealed the chemical interaction between HA powder and FCNTs. Appearance of an N 1s peak in the photoelectron spectra indicated the covalent attachment. Band deterioration is observed from slab gel-electrophoresis studies. Electrophoretic time study indicated that 20 min is required to run the DNA in column.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Synthetic Metals - Volume 159, Issues 3–4, February 2009, Pages 238–245
نویسندگان
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