کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
144480 | 438934 | 2015 | 7 صفحه PDF | دانلود رایگان |
• The impact of impurity on the growth behaviour of a crystal population is modelled.
• The study is enabled by a morphological population balance model.
• The study is for β L-glutamic acid crystals and the additive is L-phenylalanine.
• Simulation results were verified in experiments.
This short communication investigates the impact of impurity on crystal growth behaviour in terms of crystal shape distribution. A two dimensional population balance model is applied to study the crystal shape changing behaviour in cooling crystallisation producing β-form L-glutamic acid crystals, in the presence and without the presence of an additive, L-phenylalanine. The simulation results were verified in experiments using a 1-litre crystalliser for crystallisation of L-glutamic acid.
The evolution of shape distribution for the seeded crystallisation of L-glutamic acid in the presence of an impurity, L-phenylalanine. It was found that the impurity did not have much influence on the width direction, but has inhibited the growth in the length direction.Figure optionsDownload as PowerPoint slide
Journal: Advanced Powder Technology - Volume 26, Issue 2, March 2015, Pages 672–678