کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1473514 991048 2016 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bio-inspired assembling/mineralization process as a flexible approach to develop new smart scaffolds for the regeneration of complex anatomical regions
ترجمه فارسی عنوان
فرآیند مونتاژ / کانی سازی بیوشیمیایی به عنوان یک رویکرد انعطاف پذیر برای توسعه داربست های هوشمند جدید برای بازسازی مناطق آناتومیک پیچیده
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد سرامیک و کامپوزیت
چکیده انگلیسی

Bio-inspired synthesis of smart biomaterials is an emerging nano-technological approach to develop new solutions for an ever-raising number of patients affected by degenerative and disabling pathologies. Particularly for purpose of tissue regeneration, the new materials should function as scaffolds with high mimicry of host tissues, in order to instruct cells to perform their task. Due to the complexity of living tissues and limitations of the current fabrication methods, synthesis methods reproducing the biologic processes may exploit the huge information inherent in macromolecular matrices, to build complex nano-composites with regenerative ability. As an example the assembling/mineralization phenomena involved in hard tissues can be mimicked to achieve smart devices able to regenerate different tissues such as joints and periodontium. Besides, the implementation of this approach with remote activation by low magnetic fields of bio-resorbable superparamagnetic apatite nano-phases, may provide new devices enabling activation on demand suitable for non-invasive and more effective therapies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the European Ceramic Society - Volume 36, Issue 12, September 2016, Pages 2857–2867
نویسندگان
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