کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1505085 993752 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
AND logic gate application based on colorimetric screening of enzyme activity
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد سرامیک و کامپوزیت
پیش نمایش صفحه اول مقاله
AND logic gate application based on colorimetric screening of enzyme activity
چکیده انگلیسی

A simple and novel DNA and gold nanoparticle (AuNPs) based colorimetric method has been developed for efficient detection of Deoxyribonuclease I (DNase-I) activity. For the detection process, the sample that contains DNase-I, which will cleave double stranded DNA into small pieces. Furthermore, the small pieces DNA sequences and water-soluble conjugated polymer cause the AuNPs aggregation (the solution change the color from red to blue). Thus, DNase-I could be detected by naked eyes or UV/Vis. Molecular substrates can be viewed as computational devices that process physical or chemical ‘inputs’ to generate ‘outputs’ based on a set of logical operators. Based on the assay, we have presented a DNA/AuNP based, multi-readout AND logic operations.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Solid State Sciences - Volume 14, Issue 7, July 2012, Pages 870–873
نویسندگان
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