کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1507137 993836 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of superficial organic modification of MCM-41 matrices on drug delivery rate
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد سرامیک و کامپوزیت
پیش نمایش صفحه اول مقاله
Influence of superficial organic modification of MCM-41 matrices on drug delivery rate
چکیده انگلیسی

MCM-41-type mesoporous materials superficially modified were produced by a post-synthesis method with different organic groups (chloropropyl, phenyl, benzyl, mercaptopropyl, cyanopropyl and butyl groups). A comparative study of the adsorption and release of a model drug, ibuprofen, were carried out. These materials were characterised by XRD, TG, elemental analysis, FTIR, UV, N2 adsorption and 29Si and 13C-NMR. The adsorbed drug content and the delivery rate can be chosen according to the host–guest chemical interaction by choosing an adequate modification with an organic group. The specific matrices design for the insertion and delivery of drugs is possible.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Solid State Sciences - Volume 8, Issue 10, October 2006, Pages 1243–1249
نویسندگان
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