Investigation of the cytotoxicity of carbon nanotubes using hydroxyapatite as a nano-matrix towards mouse fibroblast cells

The cytotoxicity of carbon nanotubes adhered on hydroxyapatite matrix synthesized by catalytic chemical vapor deposition was investigated towards mouse fibroblast cells, using MTT assay method. The results demonstrate that carbon nanotubes adhered on hydroxyapatite matrix possess no evident short-term toxicity and can be considered biocompatible with L929 mouse fibroblast cells in culture, while the long-term negative effects, that are evidenced after reseeding, are probably due to physical rather than chemical interactions.