Development and application of inorganic bioactive ceramic nanocomposites for bone tissue remodeling

The objective of the article is to study the synthesis, animal tests and results of clinical applications of the newly proposed kind of bioactive ceramics for full bone tissue restoration—inorganic composites consisting of modified phosphate ceramics, bioactive glasses and bioactive glass-ceramic—so-called SYNTHETBONE materials. Regulation of the composition and structure of the composite can serve to adjust physicochemical and biological properties of the implant with demands of a particular surgery operation and provide the best results of the operations. The presented results demonstrate ample evidence of regulations of resorption rate and mechanism of the composite, favorable biological reaction on its implantation and prove its advantages and high efficiency in numerous surgery operations.