Runaway prevention in liquid-phase homogeneous semibatch reactors

A concept of the safety boundary diagram, elaborated in our previous studies for liquid–liquid heterogeneous reactions, has been developed here for liquid-phase homogeneous semibatch reactors. With the use of this boundary diagram, inherently safe-operating conditions can be easily determined without costly and time-consuming kinetic studies. A rapid procedure to estimate the dosing time and the cooling temperature appropriate for inherently safe operation of the reactor has been elaborated and proposed.