کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
170651 | 458406 | 2013 | 5 صفحه PDF | دانلود رایگان |
An efficient l-proline-accelerated synthesis of 9-substituted-2,3,4,9-tetrahydro-1H-xanthen-1-one derivatives has been accomplished via one-pot condensation of dimedone or 1,3-cyclohexanedione with substituted salicylaldehydes under mild reaction conditions. This protocol demonstrates several notable advantages, including operational simplicity, short reaction times, environmentally friendly conditions, no necessity of extraction and chromatographic purification steps, and high yields of the target products.
An efficient, environmentally benign and high yielding procedure has been developed for the synthesis of 9-substituted-2,3,4,9-tetrahydro-1H-xanthen-1-one derivatives via one-pot condensation of cyclic-1,3-hexanediones with salicylaldehydes in the presence of l-proline as an organocatalyst under mild reaction conditions.Figure optionsDownload as PowerPoint slide
Journal: Comptes Rendus Chimie - Volume 16, Issue 12, December 2013, Pages 1153–1157