کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
170890 | 458421 | 2013 | 6 صفحه PDF | دانلود رایگان |
A novel, greener approach was adopted for the synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives (4a–i) using bis[(L)prolinato-N,O]Zn as an inexpensive, efficient and mild Lewis acid catalyst in water. The methodology offers several advantages such as short reaction time, high yields, clean process, low loading of catalyst and simple operational procedure. The catalyst was active up to five cycles and was identified by SEM-EDX analysis.
Bis[(L)prolinato-N,O]Zn–water is found to be an efficient and recyclable catalyst in promoting one-pot, three-component reactions of aldehydes, active methylene compounds and urea to afford a series of 3,4-dihydropyrimidin-2(1H)-ones in high yields. The catalyst was active up to five cycles and was identified by SEM-EDX analysis.Figure optionsDownload as PowerPoint slide
Journal: Comptes Rendus Chimie - Volume 16, Issue 2, February 2013, Pages 183–188