کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1758681 | 1523208 | 2015 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Numerical analysis of ultrasound propagation and reflection intensity for biological acoustic impedance microscope
ترجمه فارسی عنوان
تجزیه و تحلیل عددی انتشار اولتراسوند و شدت انعکاس میکروسکوپ امپدانس آکوستیکی بیولوژیکی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
چکیده انگلیسی
This paper proposes a new method for microscopic acoustic imaging that utilizes the cross sectional acoustic impedance of biological soft tissues. In the system, a focused acoustic beam with a wide band frequency of 30-100Â MHz is transmitted across a plastic substrate on the rear side of which a soft tissue object is placed. By scanning the focal point along the surface, a 2-D reflection intensity profile is obtained. In the paper, interpretation of the signal intensity into a characteristic acoustic impedance is discussed. Because the acoustic beam is strongly focused, interpretation assuming vertical incidence may lead to significant error. To determine an accurate calibration curve, a numerical sound field analysis was performed. In these calculations, the reflection intensity from a target with an assumed acoustic impedance was compared with that from water, which was used as a reference material. The calibration curve was determined by changing the assumed acoustic impedance of the target material. The calibration curve was verified experimentally using saline solution, of which the acoustic impedance was known, as the target material. Finally, the cerebellar tissue of a rat was observed to create an acoustic impedance micro profile. In the paper, details of the numerical analysis and verification of the observation results will be described.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasonics - Volume 61, August 2015, Pages 79-87
Journal: Ultrasonics - Volume 61, August 2015, Pages 79-87
نویسندگان
Agus Indra Gunawan, Naohiro Hozumi, Sachiko Yoshida, Yoshifumi Saijo, Kazuto Kobayashi, Seiji Yamamoto,