کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1759377 1019277 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Thermal response of contrast agent microbubbles: Preliminary results from physico-chemical and US-imaging characterization
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
Thermal response of contrast agent microbubbles: Preliminary results from physico-chemical and US-imaging characterization
چکیده انگلیسی
In conclusion, we demonstrate that Sonovue® microbubbles reach their maximal diameter at 40 °C, and then a sharp decrease is observed, possible due to the occurrence of gel-sol transition of the phospholipidic shell. At the same temperature the maximal backscattering intensity is predicted and actually experimentally observed. Sonovue®, as well as other contrast agents based only on phospholipids, are, therefore, not suitable for use as non-invasive temperature monitoring medium since it is sensitive to temperatures below the hyperthermic range. Although microbubbles are in principle thermally effective, other coating materials should be investigated in order to increase their operative thermal range.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasonics - Volume 44, Supplement, 22 December 2006, Pages e127-e130
نویسندگان
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