کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
177107 | 458965 | 2011 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Facile synthesis of monofunctional pentamethine carbocyanine fluorophores Facile synthesis of monofunctional pentamethine carbocyanine fluorophores](/preview/png/177107.png)
A high-yield route to symmetric, conjugatable pentamethine carbocyanine dyes with far-red/near infrared (NIR) emission between 650 and 700 nm is reported. The dyes are prepared via condensation of indolium or benz[e]indolium inner salts with an alkyl carboxylic acid derivatized malonaldehyde dianil or alternatively in a one-pot reaction without isolation of the malonaldehyde intermediate. The fluorophores are water-soluble, have bright fluorescence emission, are easily prepared in good yield, and are promising candidates for use in a variety of biochemical and in vivo imaging applications.
Research highlights
► Water-soluble, near-infrared conjugatable symmetric carbocyanine fluorophores.
► High-yielding one-pot synthetic procedure.
► Strong fluorescence emission with improved photostability.
Journal: Dyes and Pigments - Volume 90, Issue 2, August 2011, Pages 119–122