کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1788829 1023481 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optical detection of squamous cell carcinomas ex vivo for early diagnosis of cancerous oral tissues using combined spatial variance and ratio-based determinants
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
Optical detection of squamous cell carcinomas ex vivo for early diagnosis of cancerous oral tissues using combined spatial variance and ratio-based determinants
چکیده انگلیسی

We investigate optical signatures of normal and cancer tissues by measuring nine cases of oral squamous cell carcinomas transplanted into tongue of nude mice. Transmission results were measured with a spatially translated fiber probe for auto-fluorescence spectra of normal and cancer specimens in 450–750 nm. Normal and cancer specimens were quantitatively compared based on extinction coefficients (μt) calculated by collimated transmission method. Although direct comparison of μt may be difficult to detect cancer specimens, it was found that use of multiple determinants based on spatial variance and a spectral ratio of μt shows promise for the diagnosis. The preliminary results attest the feasibility and challenges of screening precancerous oral tissues using optical detection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Applied Physics - Volume 9, Issue 4, Supplement, July 2009, Pages e206–e209
نویسندگان
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