Amperometric determination of reduced glutathione with a new Co-based metal-organic coordination polymer modified electrode

• A new 2-dimensional (2D) Co-based metal-organic coordination polymer (Co-MOCP) was prepared by a simple solvothermal synthesis.
• The as-prepared Co-MOCP exhibits excellent electrocatalytic activity towards the oxidation of reduced glutathione (GSH).
• The electrochemical sensor based on Co-MOCP shows a wide linear range and low detection limit for the determination of GSH.

This communication reports a new 2-dimensional (2D) Co-based metal-organic coordination polymer (Co-MOCP) by a simple solvothermal synthesis, and exhibits the first use of Co-MOCP as an electrode material for the electrocatalytic oxidation of reduced glutathione (GSH). The GSH electrochemical sensor based on Co-MOCP showed a wide linear range from 2.5 μM to 0.95 mM with the detection limit of 2.5 μM for the determination of GSH. This work suggests that metal-organic materials would offer a promising candidate for the potential applications in electrocatalysis and electroanalysis.

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