Microneedle-based self-powered glucose sensor

• Integration of biofuel cell into minimally-invasive microneedles.
• Harvesting sustainable power from glucose present at interstitial fluid.
• Self-powered subdermal glucose sensing without potentiostatic circuitry.
• Power signals independent of electroactive species that affect amperomentric sensors.

A microneedle-based self-powered biofuel-cell glucose sensor is described. The biofuel cell sensor makes use of the integration of modified carbon pastes into hollow microneedle devices. The system displays defined dependence of the power density vs glucose concentration in artificial interstitialfluid. An excellent selectivity against common electroactive interferences and long-term stability are obtained. The attractive performance of the device indicates considerable promise for subdermal glucose monitoring.

Figure optionsDownload as PowerPoint slide