کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1805232 1024674 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation and characterization of temperature-responsive magnetite nanoparticles conjugated with N-isopropylacrylamide-based functional copolymer
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
Preparation and characterization of temperature-responsive magnetite nanoparticles conjugated with N-isopropylacrylamide-based functional copolymer
چکیده انگلیسی

In this study, magnetite nanoparticles conjugated with the temperature-responsive N-isopropylacrylamide-based functional copolymer were prepared. Observations using a transmission electron microscope (TEM) and X-ray photoelectron spectroscopy (XPS) spectral measurements proved that the surrounding polymer layers bind to the magnetite surfaces. The particles showed a very sensitive temperature-responsive behavior, which was confirmed by particle size analysis and investigation of retention in a hydrophobic octadecylsilane (ODS)-modified column. In the magnetic field that was induced by an alternating electric current, the nanoparticles also demonstrated a sensitive temperature-responsive behavior and this result meant that the temperature-responsive polymer layer could absorb the heat induced in the magnetite cores. The temperature-responsive magnetite nanoparticles could show effective aggregation formation or hydrophobic interaction in response to an alternating magnetic field. These interesting phenomena would be used for embolization therapy or targeted drug delivery aiming at a cancer treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetism and Magnetic Materials - Volume 302, Issue 2, July 2006, Pages 327–333
نویسندگان
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