کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1806880 | 1025233 | 2011 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Limitations of the permeability-limited compartment model in estimating vascular permeability and interstitial volume fraction in DCE-MRI
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Our results suggest that the permeability-surface-limited compartment model generally underestimates capillary permeability for capillaries with a radius of 4 μm by factors from â0.03 for α=0.04, to â 0.1 for α=0.2, to â 0.5 for α=1.0. An overestimation of actual capillary permeability for capillaries with a radius of 12 μm by a factor of â¥1.3 was found for α=1.0, while α=0.2 yielded an underestimation by a factor of â0.3 and α=0.04 by a factor of â 0.03. The interstitial volume fraction, ve, obtained by the compartment model differed with increasing intercapillary distances and for low vessel permeability, whereas ve was found to be estimated approximately accurately for P=0.3 μm/s and P=3.3 μm/s for vessel distances <100 μm.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 29, Issue 5, June 2011, Pages 639-649
Journal: Magnetic Resonance Imaging - Volume 29, Issue 5, June 2011, Pages 639-649
نویسندگان
Guido Correia Carreira, Ole Gemeinhardt, Rudolf Gorenflo, Dirk Beyersdorff, Tobias Franiel, Johanna Plendl, Lutz Lüdemann,