کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1807177 1025247 2009 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Functional magnetic resonance imaging brain activation directly from k-space
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
Functional magnetic resonance imaging brain activation directly from k-space
چکیده انگلیسی

In functional magnetic resonance imaging (fMRI), the process of determining statistically significant brain activation is commonly performed in terms of voxel time series measurements after image reconstruction and magnitude-only time series formation. The image reconstruction and statistical activation processes are treated separately. In this manuscript, a framework is developed so that statistical analysis is performed in terms of the original, prereconstruction, complex-valued k-space measurements. First, the relationship between complex-valued (Fourier) encoded k-space measurements and complex-valued image measurements from (Fourier) reconstructed images is reviewed. Second, the voxel time series measurements are written in terms of the original spatiotemporal k-space measurements utilizing this k-space and image relationship. Finally, voxelwise fMRI activation can be determined in image space in terms of the original k-space measurements. Additionally, the spatiotemporal covariance between reconstructed complex-valued voxel time series can be written in terms of the spatiotemporal covariance between complex-valued k-space measurements. This allows one to utilize the originally measured data in its more natural, acquired state rather than in a transformed state. The effects of modeling preprocessing in k-space on voxel activation and correlation can then be examined.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 27, Issue 10, December 2009, Pages 1370–1381
نویسندگان
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