کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1807362 1025258 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Occipital lobe's cortical thinning in ametropic amblyopia
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
Occipital lobe's cortical thinning in ametropic amblyopia
چکیده انگلیسی

Background and PurposeThe present study was designed to detect the abnormalities of the cortical thickness in children with ametropic amblyopia by a computer-aided MRI technique.MethodsNine children with ametropic amblyopia and eight age-matched normal controls underwent MRI brain scanning that was performed on a Siemens Avanto 1.5-T scanner, and standard T1-weighted high-resolution anatomic scans of magnetization-prepared rapid gradient echo (MPRAGE) sequence were obtained. For the cortical thickness analysis, 3D MPRAGE images were processed with FreeSurfer software package (http://www.nmr.mgh.harvard.edu/freesurfer/), and the cortical thicknesses were compared between the patient group and the normal control group.ResultsThe cortical thicknesses of the lingual and pericalcarine areas in the left hemisphere and of the cuneus, lateraloccipital and lingual areas in the right hemisphere in the amblyopic group were significantly thinner than those of the control group (P<.05).ConclusionThe changes in cortical thickness of several occipital regions in amblyopic patients may be important in the diagnosis and treatment of this disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 27, Issue 5, June 2009, Pages 637–640
نویسندگان
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