کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
180757 459388 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Spatiotemporal sub-cellular biopatterning using an AFM-assisted electrochemical system
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Spatiotemporal sub-cellular biopatterning using an AFM-assisted electrochemical system
چکیده انگلیسی

The integration of electrochemical-based biolithography (ECBL) with an ordinary atomic force microscope (AFM) enables in situ lithography adjacent to a single, cultured cell, consequently allowing the morphological shape of the cell to be manipulated. The tip of a commercially available AFM cantilever was modified to serve as an electrode that could generate the oxidant HBrO for local, controlled etching of a cytophobic material (heparin or albumin) previously layered adjacent to a living cell. A NIH-3T3 fibroblast, initially confined to a patterned area, extended along a bioadhesive surface that had been newly exposed using the ECBL-AFM system.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochemistry Communications - Volume 11, Issue 9, September 2009, Pages 1781–1784
نویسندگان
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