کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1807582 1025267 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
T2 relaxation induced by clusters of superparamagnetic nanoparticles: Monte Carlo simulations
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
T2 relaxation induced by clusters of superparamagnetic nanoparticles: Monte Carlo simulations
چکیده انگلیسی

Clustering strongly affects the transverse (T2) relaxation induced by superparamagnetic nanoparticles in magnetic resonance experiments. In this study, we used Monte Carlo simulations to investigate systematically the relationship between T2 values and the geometric parameters of nanoparticle clusters. We computed relaxation as a function of particle size, number of particles per cluster, interparticle distance, and cluster shape (compact vs. linear). We found that compact clusters induced relaxation equivalent to similarly sized single particles. For small particles, the shape and density of clusters had a significant effect on T2. In contrast, for larger particles, T2 relaxation was relatively independent of cluster geometry until interparticle distances within a cluster exceeded ten times the particle diameter. Results from our simulations suggest principles for the design of nanoparticle aggregation-based sensors for MRI.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 26, Issue 7, September 2008, Pages 994–998
نویسندگان
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