کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1807945 1025297 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Diffusion tensor imaging of native and degenerated human articular cartilage
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
Diffusion tensor imaging of native and degenerated human articular cartilage
چکیده انگلیسی

Diffusion tensor imaging (DTI) is potentially sensitive to collagen degeneration in cartilage. In this study, DTI was measured on human cartilage samples with interventions of trypsin and collagenase. The measured preferred diffusion direction was consistent with the zonal structure of collagen network. The glycosaminoglycan concentration decreased and apparent diffusion coefficient increased with both interventions. The fractional anisotropy (FA) was not affected by trypsin and showed a slight increase with combined trypsin and collagenase intervention. DTI in cartilage is technically challenging due to the low FA and the almost undetectable change with collagen disruption seen here.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 25, Issue 2, February 2007, Pages 168–171
نویسندگان
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