کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
181941 459413 2007 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrochemical degradation of quercetin: Isolation and structural elucidation of the degradation products
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Electrochemical degradation of quercetin: Isolation and structural elucidation of the degradation products
چکیده انگلیسی

This paper reports the first complete isolation, characterization and structural elucidation of 18 intermediates following the electrochemical oxidation of quercetin and provides a mechanism of reaction. Bulk electrolysis was employed to induce the oxidation of quercetin in ethanol–PBS buffered neutral solution (1:1, v/v, pH 7.40). Simultaneous UV–Vis, cyclic and differential pulse voltammetric studies indicated the formation of new products due to the induced electrochemical oxidation of quercetin. Preparative separation and the verification of the oxidized products were achieved using a combination of column chromatography, GC–MS and LC–MS–MS analyses. A possible mechanism for the degradation pathways of quercetin was proposed including an electrochemical step leading to the formation of semi-quinone, ortho-quinone and quinone methide, as well as a chemical step corresponding to the formation of complex degradation products of taxifolin, depside, small phenolic acids, quercetin–ethanol adduct, benzofuronone and dimer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochemistry Communications - Volume 9, Issue 9, September 2007, Pages 2246–2255
نویسندگان
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