کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1831174 1027493 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Photon-counting H33D detector for biological fluorescence imaging
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم ابزار دقیق
پیش نمایش صفحه اول مقاله
Photon-counting H33D detector for biological fluorescence imaging
چکیده انگلیسی

We have developed a photon-counting High-temporal and High-spatial resolution, High-throughput 3-Dimensional detector (H33D) for biological imaging of fluorescent samples. The design is based on a 25 mm diameter S20 photocathode followed by a 3-microchannel plate stack, and a cross-delay line anode. We describe the bench performance of the H33D detector, as well as preliminary imaging results obtained with fluorescent beads, quantum dots and live cells and discuss applications of future generation detectors for single-molecule imaging and high-throughput study of biomolecular interactions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment - Volume 567, Issue 1, 1 November 2006, Pages 133–136
نویسندگان
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