کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1887805 | 1043611 | 2007 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Monte-Carlo-Modell der Aerosolbolusdispersion in der menschlichen Lunge - Teil 1: Theoretische Modellbeschreibung und Anwendung
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موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Monte-Carlo-Modell der Aerosolbolusdispersion in der menschlichen Lunge - Teil 1: Theoretische Modellbeschreibung und Anwendung Monte-Carlo-Modell der Aerosolbolusdispersion in der menschlichen Lunge - Teil 1: Theoretische Modellbeschreibung und Anwendung](/preview/png/1887805.png)
چکیده انگلیسی
Aerosol bolus dispersion, which has excited enormous interest in lung medicine due to its possible use as an efficient tool for the non-invasive clinical diagnosis of lung function, was simulated by a Monte Carlo model based on the concept of effective diffusivities and a stochastic lung geometry. The mathematical approach enabled the computation of essential characteristics of the exhaled bolus (half width, standard deviation, skewness, and mode shift) as well as the estimation of their dependence upon the volumetric lung depth (VLD) of the inhaled bolus. Results of the dispersion model generally show a very good correspondence with preliminary published experimental data. Half width and standard deviation of the exhaled bolus increase with VLD according to specific functions, whereas skewness and mode shift are subject to a decrease. While no correlation between bolus dispersion and flow rate could be worked out with the model, dispersion linearly increased with total lung capacity (TLC).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Zeitschrift für Medizinische Physik - Volume 17, Issue 2, 15 June 2007, Pages 127-135
Journal: Zeitschrift für Medizinische Physik - Volume 17, Issue 2, 15 June 2007, Pages 127-135
نویسندگان
Robert Sturm, EÅzbieta PawÅak, Werner Hofmann,