کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1897542 1044546 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evolving towards the hypercycle: A spatial model of molecular evolution
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
Evolving towards the hypercycle: A spatial model of molecular evolution
چکیده انگلیسی

We extend earlier cellular automata models of spatially extended hypercycles by including an explicit genetic component in the model. This allows us to study the sequence evolution of hypercyclically coupled molecular replicators in addition to considering their population dynamics and spatial organization. In line with previous models that considered either spatial organization or sequence evolution alone, we find both temporal oscillations of the relative concentration of the species forming the hypercycles as well as the formation of spatial organizations including spiral waves. We also confirm the greatly increased robustness of the spatially extended hypercycle against various classes of parasites.We determine how the sequence evolution of each of the hypercyclically coupled populations proceeds (after an initial selection-dominated phase) in a drift-like manner that can be described by a diffusion process in sequence space. Kimura’s theory of neutral evolution is therefore applicable on long timescales despite the fact that the hypercycle exhibits extreme periodic changes in population sizes that are governed solely by frequency-dependent selection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica D: Nonlinear Phenomena - Volume 217, Issue 2, 15 May 2006, Pages 134–141
نویسندگان
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