کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1899785 1045140 2010 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A new traveling wave phenomenon of Dictyostelium in the presence of cAMP
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
A new traveling wave phenomenon of Dictyostelium in the presence of cAMP
چکیده انگلیسی

The emergence of wave patterns in chemical and biological systems is of interest for the understanding of development, differentiation, signaling, and other phenomena. In this work we report a new type of wave pattern - called the “global wave” - which was observed in populations of Dictyostelium discoideum cells exposed to an excess of cyclic adenosine- 3′, 5′- monophosphate (cAMP) added to the supporting agar. It has been found that the addition of different amounts of cAMP to the agar leads to important deviations from the standard course of aggregation: (i) the formation and propagation of a global wave that has not been observed before; (ii) the delayed onset or absence of cAMP waves patterning; (iii) an atypical mechanism of cells clustering; and (iv) a faster or incomplete developmental cycle. We suggest that the global wave is a chemotactic response of the Dictyostelium cells to a wave of the cAMP concentration.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica D: Nonlinear Phenomena - Volume 239, Issue 11, 1 June 2010, Pages 879–888
نویسندگان
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