Effets sur les fonctions cognitives et mnésiques de sujets sains d'un hydrolysat de protéines de poisson (FPHD800)Â : étude comparative avec le ginkgo biloba (EGB 761®)

A comparative study was an open study conducted on a population of 150 people, men and women between 45 and 65 years of age, who consulted the center because of a memory complaint. Involved three subject groups: a control group, a group receiving EGb 761® (Ginkgo biloba) and a group receiving fish protein hydrolysate enriched in DHA (FPHD800). After assessment of deficits related to the memory complaint using the Mac Nair scale, Le Poncin Gym-Cerveau®, Weschler digit SPAN test and Rey 15 words test, three randomized groups every 10 subjects of 50 subjects each were formed on t 0 to constitute one control group (without treatment), one group treated with EGb 761® (Ginkgo biloba) at three capsules per day and one group treated with FPHD800 at six capsules per day. The following evaluation criteria for memory performances used in this study were memory complaint, memory fatigability and visual and auditory memorization, immediate and in a learning situation. These evaluations were carried out at the start of the study and were repeated in equivalent relations after 30 and 60 days in the three groups. The statistical analysis of the results (Student's t-test for paired and non-paired data as well as a factorial analysis of variance ANOVA) showed for each criteria adopted that the consumption of 1200 mg per day of FPHD800 containing 600 mg of fish protein hydrolysate, 260 mg de docosahexaenoic acid (DHA) and 1.5 mg of vitamin E, improved memory functions compared to the control group and also to the group treated with EGb 761®. This improvement in memory performances was significant after one month of treatment and highly significant after two months.