کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1922547 1048813 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dopamine dysregulation syndrome, addiction and behavioral changes in Parkinson's disease
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Dopamine dysregulation syndrome, addiction and behavioral changes in Parkinson's disease
چکیده انگلیسی

Degeneration of the dopaminergic system in Parkinson's disease and longstanding exposure to dopaminergic drugs may cause reward system malfunction. This may manifest as addiction to l-dopa and behavioral disturbances associated with the impulse control system. These disturbances include: gambling, excessive spending (shopping), hypersexuality and binge eating. We included one such patient's personal story to emphasize the devastating consequences of these potentially reversible phenomena: the patient describes in his own words how gambling induced by an exposure dopamine agonist therapy significantly worsened his disease-related difficulties.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Parkinsonism & Related Disorders - Volume 14, Issue 4, May 2008, Pages 273–280
نویسندگان
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