کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1923666 | 1048906 | 2013 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Remobilization through stretching improves gait recovery in the rat
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کلمات کلیدی
H.E.PBSTBSTECLECMBSA - BSATris-buffered saline with Tween 20 - Tris-buffered saline با Tween 20bovine serum albumin - آلبومین سرم گاوImmobilized - امولسیون شدهImmobilization - ایمن سازیenhanced chemiluminescence - بهبود شیمیایی لومنMuscle stretching exercises - تمرینات کششی عضلاتRange of motion - دامنه حرکتVersus - در مقابلvs. - در مقابل.ROM - رامgait - راه رفتنExtracellular matrix - ماتریکس خارج سلولیPhosphate-buffered saline - محلول نمک فسفات با خاصیت بافریMorphology - مورفولوژی(ریخت شناسی)Rat - موش صحراییhematoxylin–eosin - هماتوکسیلین ائوزین
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Remobilization of a previously immobilized rat right hindlimb in the ankle plantar-flexion-shortened position by free movement alone or associated with intermittent passive stretching was assessed by analysis of gait variables and dorsiflexion range of motion. The variables were related with the expression of extracellular matrix proteins and the addition of serial sarcomeres. Sixty-four female Wistar rats were divided into 8 groups: immobilized, free for 10 days, immobilized/stretched/free for 1, 3 or 10 days, immobilized/free for 1, 3 or 10 days. Gait variables, range of motion, serial sarcomeres number, localization and staining intensity of fibronectin, and expressions of types I and III collagen were analyzed. The hypokinesia changed the functional variables of gait, reduced the dorsiflexion range of motion (ROM), increased the number of fibers with intracellular fibronectin/total number of fibers (FIF/TNF), and decreased the expression of the type I collagen. After three days, morphological changes were exacerbated and the number of serial sarcomeres was increased in both groups, immobilized/stretched/free and immobilized/free. Functional impairment, ROM restriction and increased FIF/TNF were also observed. Despite the above described alterations, 10 days of stretching program increased the effectiveness of remobilization leading to recovery of the abnormalities observed in the muscle.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Histochemica - Volume 115, Issue 5, June 2013, Pages 460-469
Journal: Acta Histochemica - Volume 115, Issue 5, June 2013, Pages 460-469
نویسندگان
LetÃcia Oliveira Cação-Benedini, Paula Guilherme Ribeiro, Anna Raquel Silveira Gomes, Julye Leiko Ywazaki, Vanessa Vilela Monte-Raso, Cibele Maria Prado, Ana Claudia Mattiello-Sverzut,