کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1974315 | 1060348 | 2006 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cloning of the promoter from the gonadal aromatase gene of the European sea bass and identification of single nucleotide polymorphisms
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Aromatase contributes to sex differentiation by catalysing the conversion of androgens into estrogens. We have cloned the promoter of the gonadal aromatase gene from the sea bass, Dicentrarchus labrax, a species whose farming is complicated by male-skewed sex ratios. The promoter shows a conserved binding site for SF-1 as well as two cAMP response elements (CREs) and putative binding sites for transcription factors belonging to the Sox and forkhead families. Analysis of promoter sequences from individual fish suggests the presence of three promoter alleles that arise due to three single nucleotide polymorphisms (SNPs) in linkage disequilibrium.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology - Volume 145, Issue 1, September 2006, Pages 47–53
Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology - Volume 145, Issue 1, September 2006, Pages 47–53
نویسندگان
Malyka Galay-Burgos, Claire Gealy, Laia Navarro-Martín, Francesc Piferrer, Silvia Zanuy, Glen E. Sweeney,