Characteristics of the antitumor activities in tumor cells and modulation of the inflammatory response in RAW264.7 cells of a novel antimicrobial peptide, chrysophsin-1, from the red sea bream (Chrysophrys major)

► Chrysophsin-1 induced cell membrane rupture much like a lytic peptide. ► Chrysophsin-1 induced necrosis with high-concentration treatment. ► Chrysophsin-1 inhibited tumor cell growth. ► The modulatory activity of the inflammatory response and antitumor activity of chrysophsin-1 were examined.