کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2010242 1066726 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mechanism of fenvalerate-withdrawal-dependent recovery in metabolism of a catfish, Clarias batrachus
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم زراعت و اصلاح نباتات
پیش نمایش صفحه اول مقاله
Mechanism of fenvalerate-withdrawal-dependent recovery in metabolism of a catfish, Clarias batrachus
چکیده انگلیسی
The effects of protein synthesis inhibitors on fenvalerate-withdrawal-dependent recovery in citrate synthase (CS), glucose 6-phosphate dehydrogenase (G6-PDH), lactate dehydrogenase (LDH), RNA, and protein of brain, liver, and skeletal muscle of Clarias batrachus were studied to explore possible mode of action of a pyrethroid insecticide at metabolic level. The administration of actinomycin D or cycloheximide inhibited partially or completely the withdrawal-dependent increase in enzyme activities, RNA, and protein contents, substantiating de novo synthesis of these macromolecules during recovery. The inhibition was more pronounced in response to cycloheximide reflecting recovery in translation process. This also suggests the possibility of fenvalerate-induced impairment of metabolism through inhibition of enzyme synthesis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pesticide Biochemistry and Physiology - Volume 86, Issue 3, November 2006, Pages 167-171
نویسندگان
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