کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2011673 1067012 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of n-3 polyunsaturated fatty acids on depressive symptoms, anxiety and emotional state in patients with acute myocardial infarction
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Effects of n-3 polyunsaturated fatty acids on depressive symptoms, anxiety and emotional state in patients with acute myocardial infarction
چکیده انگلیسی

BackgroundOur aim was to assess whether an early introduced n-3 polyunsaturated fatty acids (n-3 PUFA) supplementation affects depression symptoms, anxiety and emotional state in patients with acute myocardial infarction (AMI) and no history of mental disorders.MethodsFifty two patients with AMI were enrolled into the study and randomized to the study group (group P; n = 26; standard therapy + n-3 PUFA1 g daily) or the control group (group C; n = 26; standard therapy). The following psychological tests were used at the baseline (3rd day of AMI) and after one month (30 ± 1 days): Beck Depression Inventory (BDI), State-Trait Anxiety Inventory in a specific situation (STAI-S) and as a general trait (STAI-T), Emotional State Questionnaire (ESQ).ResultsThe baseline characteristics, pharmacotherapy and BDI, STAI-S/T and ESQ were similar between both groups. The mean test scores assessed for all patients (group P and C) during the one-month observation were significantly lower for BDI (p = 0.04), STAI-T (p = 0.03), STAI-S (p = 0.01) and harm/loss emotions (p = 0.005). After adjusting for age, sex, body mass index, coronary artery disease severity, ejection fraction, serum troponin level and the baseline tests results, n-3 PUFAintervention revealed additional significant decrease in BDI (p = 0.046), STAI-S (p = 0.03) and harm/loss emotions (p = 0.04).ConclusionsOur study provides novel and preliminary observations – n-3 PUFAsupplementation reveals additional decreasing effects on depressive and anxiety symptoms in early post-MI patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacological Reports - Volume 65, Issue 1, January–February 2013, Pages 59–68
نویسندگان
, , , , , , ,