Anthraquinone–steroids, evanthrasterol A and B, and a meroterpenoid, emericellic acid, from endophytic fungus, Emericella variecolor

• Two new anthraquinone–steroids and a new meroterpenoid were isolated.
• Their structures were determined by spectroscopic analysis (1D and 2D NMR).
• Emericellic acid (3) is a new skeleton of andilesin-like meroterpenoid.

Two new anthraquinone–steroids, evanthrasterol A and B (1 and 2), and a new meroterpenoid, emericellic acid (3), together with six known compounds (4–9) were isolated from an endophytic fungus, Emericella variecolor. Their structures were determined by spectroscopic analysis (1D and 2D NMR, HRESIMS and FTIR). Herein emericellic acid (3) is a new skeleton of meroterpenoid with carboxylic functional group at C-9′ and this is the first report on isolation of anthraquinone–steroids from E. variecolor.

Two new anthraquinone–steroids, evanthrasterol A and B (1 and 2), and a new meroterpenoid, emericellic acid (3), together with six known compounds (4–9) were isolated from an endophytic fungus, Emericella variecolor. Their structures were determined by comprehensive analysis of spectroscopic data (1D and 2D NMR). Emericellic acid (3) is a new skeleton of meroterpenoid with carboxylic functional group at C-9′.Figure optionsDownload as PowerPoint slide