کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2027705 1542704 2015 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sixteen novel C-21 steroidal glycosides from the roots of Cynanchum mooreanum
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Sixteen novel C-21 steroidal glycosides from the roots of Cynanchum mooreanum
چکیده انگلیسی


• Sixteen new C-21 steroidal glycosides from the roots of Cynanchum mooreanum.
• Their immunological activities against proliferation of mice splenocytes were assayed.
• It suggests that C-21 steroidal glycosides are the main constituents in Cynanchum mooreanum.

Fourteen novel 14,15-diseco-18-nor-pregnane-type steroidal glycosides, mooreanoside A–C (1–3) and mooreanoside F–P (6–16) and two new 14,15-diseco-pregnane-type steroidal glycosides, mooreanoside D–E (4–5) were isolated from the roots of Cynanchum mooreanum Hemsl. Their structures were determined on the basis of spectroscopic and chemical analysis. Compounds 1–6, 8–10, 12–14 and 16 were tested for their immunological activities in vitro against Con-A induced proliferation of mice splenocytes.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Steroids - Volume 104, December 2015, Pages 79–94
نویسندگان
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