New polyoxypregnane glycosides from the roots of Marsdenia tenacissima

• Phytochemical study on Marsdenia tenacissima roots was performed for the first time.
• Sixteen new polyoxypregnane glycosides were isolated.
• This work was helpful to further understand the constituents from M. tenacissima.

For the first time, a systematic phytochemical study was performed on the roots of Marsdenia tenacissima. Finally, sixteen new polyoxypregnane glycosides, marstenacissides A1–A7 (1–7) and marstenacissides B1–B9 (8–16), were isolated from M. tenacissima roots. The structures of these new compounds were established by various spectroscopic techniques, including 1D and 2D NMR spectroscopy and mass spectrometry.

Sixteen new polyoxypregnane glycosides (1–16) were isolated from the roots of Marsdenia tenacissima. Their structures were established by NMR spectroscopy and mass spectrometry.Figure optionsDownload as PowerPoint slide