کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2027971 | 1070386 | 2012 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Hydrogenation of ecdysteroids Hydrogenation of ecdysteroids](/preview/png/2027971.png)
Catalytic hydrogenation is extensively used in steroid chemistry. The interest in transformations to the steroid skeleton of ecdysteroids has been increasing in the past years. Essential interest in the chemistry of ecdysteroids is caused by the selective reduction of Δ7 bond with the formation of 7,8-dihydro analogues, because this process allows one to obtain modified structures with new biological activity. Catalytic hydrogenation of isolated and conjugated double bonds and functional groups in ecdysteroids derivatives has been considered in review.
► New samples of catalytic hydrogenation of ecdysteroids derivatives were reviewed.
► Formation of 7,8α-dihydroanalogs of ecdysteroids have been demonstrated.
► There is no inversion of 5-H under basic media (MeONa) of reaction.
Journal: Steroids - Volume 77, Issue 14, December 2012, Pages 1523–1529