Recent advances in cholesterol chemistry

• Substitution of a 3β-hydroxyl group of cholesterol.
• Cholesterol oxidation to 3-oxo derivatives.
• Addition to the C5–C6 double bond of cholesterol.
• Cholesterol reactions at the allylic position.
• Formation of new C–C bonds in cholesterol.

This review article presents advances in cholesterol chemistry since 2000. Various transformations (chemical, enzymatic, electrochemical, etc.) of cholesterol are presented. A special emphasis is given to cholesterol oxidation reactions, but also substitution of the 3β-hydroxyl group, addition to the C5–C6 double bond, C–H functionalization, and C–C bond forming reactions are discussed.

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