کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2028162 1070398 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Spirostanol tetraglycosides from Ypsilandra thibetica
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Spirostanol tetraglycosides from Ypsilandra thibetica
چکیده انگلیسی

Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained five new spirostane glycosides, ypsilandrosides H-L (1–5), and a known saponin polyphylloside III (6). Among them, 1 and 2 are the first spirostane glycosides which possess novel 5(6 → 7) abeo-steroidal aglycones. Compounds 3 and 4 are rare saponins whose aglycones contain a hydroxyl group at C-7. Their structures were elucidated on the basis of MS, 1D and 2D NMR spectroscopic analysis and chemical evidences. The isolated compounds were evaluated for their cytotoxic activity on five tumor cell lines.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Steroids - Volume 75, Issue 12, December 2010, Pages 982–987
نویسندگان
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