کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2029149 1542708 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Spirostanol steroids from the roots of Allium tuberosum
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Spirostanol steroids from the roots of Allium tuberosum
چکیده انگلیسی


• Six furostanol saponins, including three new ones were isolated from the roots of Allium tuberosum.
• Three saponins exhibited potent antibacterial activities against Bacillus subtilis and Escherichia coli.
• The relationship between the antibacterial activities and the structures of these saponins is described.

Three new spirostanol saponins named tuberosines A–C (1–3), together with three known ones tuberoside O (4), 25(S)-Schidigera-saponin D5 (5), and shatavarin IV (6) were isolated from the roots of Allium tuberosum. Their structures were established on the basis of extensive spectroscopic analyses. Whereas compounds 5 and 6 exhibited potent antibacterial activities against Bacillus subtilis (32 μg/mL) and Escherichia coli (16 μg/mL), the new saponin 2 showed only moderate antibacterial activities against these pathogens. The relationship between the antibacterial activities and the structures of these saponins are described.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Steroids - Volume 100, August 2015, Pages 1–4
نویسندگان
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