کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2029518 1542742 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ergosterimide, a new natural Diels–Alder adduct of a steroid and maleimide in the fungus Aspergillus niger
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Ergosterimide, a new natural Diels–Alder adduct of a steroid and maleimide in the fungus Aspergillus niger
چکیده انگلیسی

Ergosterimide (1), a natural Diels–Alder adduct of ergosteroid and maleimide, was characterized from the culture extract of Aspergillus niger EN-13, an endophytic fungus isolated from the marine brown alga Colpomenia sinuosa. In addition, four known steroids including (22E,24R)-ergosta-5,7,22-trien-3β-ol (2), (22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (3), (22E,24R)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (4), and (22E,24R)-ergosta-7,22-dien-3β,5α,6β-triol (5) were also isolated and identified. The structures of these compounds were elucidated by extensive analysis of 1D and 2D NMR and IR spectra and MS data. The plausible biosynthetic pathway of 1 was also discussed. To the best of our knowledge, 1 is the first natural Diels–Alder adduct of steroid and maleimide reported so far.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Steroids - Volume 72, Issues 9–10, September 2007, Pages 723–727
نویسندگان
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