Lack of correlation between ERCC1 (C8092A) Single Nucleotide Polymorphism and efficacy/toxicity of platinum based chemotherapy in Chinese patients with advanced Non-Small Cell Lung Cancer

Excision repair cross-complementing group 1 (ERCC1) showed controversial results in different studies that have been carried out until now. In our Chinese population there is no correlation between ERCC1 C8092A SNP and efficacy or toxicity. Ethnicity could be a possible explanation for these controversial results.