کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2037270 1072309 2009 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis
چکیده انگلیسی

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the authors. Our study reported that miR-31 is a regulator of multiple mRNAs important for different aspects of breast cancer metastasis. We recently identified concerns with several figure panels in which original data were compiled from different replicate experiments in order to assemble the presented figure. The scope of the figure preparation issues includes compiling data from independent experiments to present them as one internally controlled experiment, statistical analyses based on technical replicates that are not reflective of the biological replicates, and comparisons of selectively chosen data points from multiple experiments. As many of the published figures are therefore not appropriate or accurate representations of the original data, we believe that the responsible course of action is to retract the paper. We apologize for any inconvenience we have caused.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 137, Issue 6, 12 June 2009, Pages 1032-1046