کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2047772 1074028 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Profiling the IgOme: Meeting the challenge
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Profiling the IgOme: Meeting the challenge
چکیده انگلیسی

The entire repertoire of antibodies in our serum, the IgOme, is a historical record of our past experiences and a reflection of our immune status at any given moment. Understanding the dynamics of the IgOme and how the diversity and specificities of serum antibodies change in response to disease and maintenance of homeostasis can directly impact the ability to design and develop novel vaccines, diagnostics and therapeutics. Here we review both direct and indirect methodologies that are being developed to map the complexity and specificities of the antibodies in polyclonal serum – the IgOme.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 588, Issue 2, 21 January 2014, Pages 318–325
نویسندگان
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