Structure and nucleotide specificity of Staphylococcus aureus dihydrodipicolinate reductase (DapB)

► The crystal structure of S. aureus dihydrodipicolinate reductase was solved at 1.8 Å resolution. ► This enzyme differs from its homologues in co-factor specificity. ► This enzyme can adopt conformational changes even in the absence of a bound substrate or co-factor.